Boston is the capital of and largest city in Massachusetts, and is one of the oldest cities in the United States. The largest city in New England, Boston is regarded as the unofficial "Capital of New England" for its economic and cultural impact on the entire "New England" region. The city proper had a 2009 estimated population of 645,169, making it the twentieth largest in the country. It is also the anchor of a substantially larger metropolitan area called  "Greater Boston", home to 4.5 million people and the tenth-largest metropolitan area in the country. Greater Boston as a commuting region includes six Massachusetts counties:  "Essex", "Middlesex","Norfolk", "Suffolk", "Plymouth", "Worcester", northern "Bristol" County, all of "Rhode Island" and parts of "New Hampshire"; it is home to 7.6 million people, making it the fifth-largest Combined Statistical Area in the United States.

Southampton is the largest city in the county of Hampshire on the south coast of England, and is situated 120 kilometres (75 mi) south-west of London and 30 kilometres (19 mi) north-west of Portsmouth. Southampton is a major port and the closest city to the New Forest. It lies at the northernmost point of Southampton Water at the confluence of the River Test and River Itchen, with the River Hamble joining to the south of the urban area. The local authority is Southampton City Council, which is a unitary authority. Just over a quarter of the jobs available in the city are in the health and education sector. A further 19 per cent are property and other business and the third largest sector is wholesale and retail, which accounts for 16.2 percent. Between 1995 and 2004, the number of jobs in Southampton has increased by 18.5 per cent. Southampton has always been a port, and the docks have long been a major employer in the city. In particular, it is a port for cruise ships; its heyday was the first half of the 20th century, and in particular the inter-war years, when it handled almost half the passenger traffic of the UK. Today it remains home to luxury cruise ships, as well as being the largest freight port on the Channel coast and fourth largest UK port by tonnage, with several container terminals. Unlike some other ports, such as Liverpool, London, and Bristol, where industry and docks have largely moved out of the city centres leaving room for redevelopment, Southampton retains much of its inner-city industry.

New York City is the most populous city in the United States and the center of the New York metropolitan area. The city has a significant impact on global commerce, finance, media, culture, art, fashion, research, education, and entertainment. As host of the United Nations Headquarters, it is also an important center for international affairs. The city is often referred to as ''New York City'' or the ''City of New York'', to distinguish it from the state of New York, of which it is a part. Located on a large natural harbor on the Atlantic coast of the Northeastern United States, New York City consists of five boroughs: The Bronx, Brooklyn, Manhattan, Queens, and Staten Island. 

Miami is a major city located on the Atlantic coast in southeastern Florida and the county seat of Miami-Dade County, the most populous county in Florida and the eighth-most populous county in the United States with a population of 2,500,625. The 42nd largest city in the United States, with a population of 433,136, it is the principal, central, and most populous city of the South {Florida} metropolitan area, the most populous metropolis in the Southeastern United States. According to the US Census Bureau, Miami's metro area is the seventh most populous in the United States, with an estimated population of 5,547,051 in 2009. 

Port Canaveral is a cruise, cargo and naval port in Brevard County, Florida, United States. It is one of the busiest cruise ports in the world with 3.9 million cruise passengers passing through during 2014. As a deep water cargo port, it has a high volume of traffic. Over 3,000,000 short tons (2,700,000 t) of bulk cargo moves through each year. Common cargo includes cement, petroleum and aggregate. The port has conveyors and hoppers for loading products directly into trucks, and facilities for bulk cargo containers. The channel is about 44 feet (13 m) deep. The port exports fresh citrus; bulk frozen citrus juice stored in one of the largest freezer warehouses in the state; cement and building materials. Ten ships, on average, enter the port each day.