Split is the largest Dalmatian city, the second-largest urban centre in Croatia, and the seat of Split-Dalmatia County. The city is located on the shores of the Mediterranean, more specifically on the eastern shore of the Adriatic Sea, spreading over a central peninsula and its surroundings, with its metropolitan area including the many surrounding seaside towns as well. An intraregional transport hub, the city is a link to the numerous surrounding Adriatic islands and the Apennine peninsula, as well as a popular tourist destination. Split is also one of the oldest cities in the area, and is traditionally considered just over 1,700 years old, while archaeological research relating to the ancient Greek colony of Aspálathos establishes the city as being several hundred years older.

Heraklion is the largest city and the administrative capital of the island of Crete. It is the fourth largest city in Greece. The Bronze Age palace of Knossos, also known as the Palace of Minos, is located nearby. Heraklion is close to the ruins of the palace of Knossos, which in Minoan times was the largest centre of population on Crete. Though there is no archaeological evidence of it, Knossos may well have had a port at the site of Heraklion as early as 2000 BC. Around the city can be found several sculptures, statues and busts commemorating significant events and figures of the city's and island's history, like El Greco, Vitsentzos Kornaros, Nikos Kazantzakis and Eleftherios Venizelos.

Dubrovnik is a gorgeous Croatian city on the Adriatic Sea coast positioned at the terminal end of the Isthmus of Dubrovnik. It is one of the most prominent tourist resorts of the Mediterranean and listed as a UNESCO World Heritage Site since 1979. The city is nicknamed "Pearl of the Adriatic". The success of Dubrovnik’s tourist industry has brought a certain degree of complacency and self-satisfaction. Certain aspects of the city’s appeal remain immune to tourist numbers, however, most notably the uniquely stunning setting and the unjaded straightforwardness of the Dubrovčani themselves.

Katakolon, or Katakolo is a seaside town in the municipality of Pyrgos in western Elis, Greece. It is situated on a headland overlooking the Ionian Sea and separating the Gulf of Kyparissia from the rest of the Ionian. It is 11 km west of downtown Pyrgos. The small village of Agios Andreas, which in ancient times was the natural harbour for Ancient Olympia, lies northwest of Katakolo. A railway connects Katakolo with Pyrgos and Olympia, but along with the rest of the rail network in the Peloponnese, services have been suspended since 2011 for economic reasons.

Venice is a city in northeastern Italy sited on a group of 118 small islands separated by canals and linked by bridges. The city is renowned for the beauty of its setting, its architecture, and its artwork. The city in its entirety is listed as a World Heritage Site, along with its lagoon. Venice has been known as the La Dominante, Serenissima, Queen of the Adriatic, City of Water, City of Masks, City of Bridges, The Floating City, and City of Canals. It has also been described as being one of Europe's most romantic cities. It is truly an amazing, stunning and interesting city for the adventurous to explore!

Messina is a harbor city in northeast Sicily, Italy. It is the capital of the Italian Metropolitan City of Messina, and has close ties with Reggio Calabria. The city's main resources are its seaports (commercial and military shipyards), cruise tourism, commerce, and agriculture (wine production and cultivating lemons, oranges, mandarin oranges, and olives). The city has been a Roman Catholic Archdiocese and Archimandrite seat since 1548 and is home to a locally important international fair. The city has the University of Messina, founded in 1548 by Ignatius of Loyola. Messina has a light rail system, Tranvia di Messina, that was opened on 3 April 2003. This line is 7.7 kilometres (4.8 mi) and links the city's central railway station with the city centre and harbour. The city is home to a significant Greek-speaking minority, rooted in its history and officially recognised.

Naples is a city in Italy; it is the capital of the region of Campania and of the province of Naples. Known for its rich history, art, culture, architecture, music, and gastronomy, Naples has played an important role in the Italian peninsula and beyond for much of its existence, which began more than 2,800 years ago. Situated on the west coast of Italy by the Gulf of Naples, the city is located halfway between two volcanic areas, Mount Vesuvius and the Phlegraean Fields. Naples has the fourth-largest urban economy in Italy, after Milan, Rome and Turin. It is the world's 103rd-richest city by purchasing power, with an estimated 2011 GDP of US$83.6 billion. The port of Naples is one of the most important in Europe, and has the world's second-highest level of passenger flow, after the port of Hong Kong. The city has long been a major cultural centre with a global sphere of influence, particularly during the Renaissance and Enlightenment eras. In the immediate vicinity of Naples are numerous culturally and historically significant sites, including the Palace of Caserta and the Roman ruins ofPompeii and Herculaneum. Culinarily, it is synonymous with pizza, which originated in the city.

Kuşadası is a coastal resort town in the Aydin Province of Aegean Turkey. It has become a popular holiday resort, especially for visitors from Northern and Western Europe. It has about 50,000 residents, although that grows significantly during the high season from May to October. The lovely city caters to tourists, growing to over half a million during the high season, when the large resort fills with tourists (from Turkey itself, northern Europe and the Balkans) plus the hotel staff, bar staff, construction workers, and drivers who are needed to work in the restaurants servicing all these visitors. The hills behind Kuşadasi are built up with big hotels and blocks of holiday flats.

Civitavecchia is a town and comune of the Metropolitan City of Rome in the central Italian region of Lazio. A sea port on the Tyrrhenian Sea, the name ''Civitavecchia'' means "ancient town". The modern city was built over a pre-existing Etruscan settlement. The massive Forte Michelangelo was first commissioned from Donato Bramante by Pope Julius II, to defend the port of Rome. The upper part of the "maschio" tower, however, was designed by Michelangelo, whose name is generally applied to the fortress. North of the city at Ficoncella are the Terme Taurine baths frequented by Romans and still popular with the Civitavecchiesi. The modern name stems from the common fig plants among the various pools. And also next to the town is the location of the cruise ship docks. All major cruise lines start and end their cruises at this location, and others stop for shore excursion days that allow guests to see Rome and Vatican sights, which are ninety minutes away.