Boston is the capital of and largest city in Massachusetts, and is one of the oldest cities in the United States. The largest city in New England, Boston is regarded as the unofficial "Capital of New England" for its economic and cultural impact on the entire "New England" region. The city proper had a 2009 estimated population of 645,169, making it the twentieth largest in the country. It is also the anchor of a substantially larger metropolitan area called  "Greater Boston", home to 4.5 million people and the tenth-largest metropolitan area in the country. Greater Boston as a commuting region includes six Massachusetts counties:  "Essex", "Middlesex","Norfolk", "Suffolk", "Plymouth", "Worcester", northern "Bristol" County, all of "Rhode Island" and parts of "New Hampshire"; it is home to 7.6 million people, making it the fifth-largest Combined Statistical Area in the United States.

Liverpool is an important city of Merseyside, England. It was founded as a borough in 1207 and was granted city status in 1880. It is a major city famed for culture, football teams, The Beatles and buzzing nightlife. It lies within the historic county boundaries of Lancashire. It is also a large, vibrant city with great cultural heritage and was awarded the title of European Capital of Culture 2008, with the famous Pier Head Waterfront being a UNESCO World Heritage site since 2004.

Halifax, legally known as the Halifax Regional Municipality (HRM), is the capital of the province of Nova Scotia, Canada. It is a major economic centre in Atlantic Canada with a large concentration of government services and private sector companies. Major employers and economic generators include the Department of National Defence, Dalhousie University,Saint Mary's University, the Halifax Shipyard, various levels of government, and the Port of Halifax. Agriculture, fishing, mining, forestry and natural gas extraction are major resource industries found in the rural areas of the municipality. Halifax was ranked as the fourth best place to live in Canada for 2012, placed first on a list of "large cities by quality of life" and placed second in a list of "large cities of the future''. Additionally, Halifax has consistently placed in the top 10 for business friendliness of North and South American cities. Waterfront warehouses known as the Historic Properties recall Halifax’s days as a trading hub for privateers, notably during the War of 1812.

St. John's is the capital and largest city in Newfoundland and Labrador, Canada. St. John's was incorporated as a city in 1888, yet is considered by some to be the oldest English-founded city in North America. Situated on the eastern tip of the Avalon Peninsula on the island of Newfoundland, it is one of the world's top ten oceanside destinations. Its name has been attributed to the feast day of John the Baptist, when John Cabot was believed to have sailed into the harbour in 1497, and also to a Basque fishing town with the same name.

Dublin is the largest and capital city of Ireland. The English name is derived from the Irish name Dubh Linn, meaning "black pool". It is a primate city with an urban population of over 1 million, containing almost 25% of the country's population. Dublin is situated near the midpoint of Ireland's east coast, at the mouth of the River Liffey, and at the centre of the Dublin Region. The city is listed by the Globalization and World Cities Research Network (GaWC) as a global city, with a ranking of "Alpha-", placing it among the top thirty cities in the world. It is a historical and contemporary centre for education, the arts, administration, economy and industry.

Rotterdam is the second-largest city in the Netherlands and the largest port in Europe. Starting as a dam on the Rotte river, Rotterdam has grown into a major international commercial centre. Its strategic location at the Rhine-Meuse-Scheldt delta on the North Sea and at the heart of a massive rail, road, air and inland waterway distribution system extending throughout Europe means that Rotterdam can rightly be called the gateway to Europe. Located in the Province of South Holland, Rotterdam is in the west of the Netherlands and at the south of the Randstad. The population of the city proper was 603,425 in March 2010. The population of the greater Rotterdam area, called "Rotterdam-Rijnmond" or just "Rijnmond", is around 1.3 million people. Rotterdam is one of Europe's most vibrant and multicultural cities.